HS-LS3.A: Inheritance of Traits


  • HS-LS3.A: Inheritance of Traits Lab Experiment
    Recombinant Paper Plasmids
    Free Lesson Plan
    Free Video
     
    Lab
    Biomedical engineers use recombinant DNA technologies with the goal of curing genetic diseases & cancer, and to improve agricultural yields. Students will model several of the steps of restriction enzymes to build plamids.
    NGSS Standard
    HS-LS3-1
    		  
    Published by Ely Science Center
  • HS-LS3.A: Inheritance of Traits Worksheet
    DNA Fingerprinting Crime Scene
    Free Lesson Plan
     
    Worksheet
    Students will examine crime scene evidence to determine who is responsible for eating the Queen's special imported Lindbergher Cheese. Students will model the process of electrophoresis and DNA fingerprinting.
    NGSS Standard
    HS-LS3-1
    		  
    Published by Shannan Muskopf
  • HS-LS3.A: Inheritance of Traits Worksheet
    Genetic Ethics Questions
    Free Lesson Plan
     
    Worksheet
    Students answer multiple choice questions on science ethics relating to genetics (cloning, gene therapy). The class then discusses the pros and cons of each of the questions.
    NGSS Standard
    HS-LS3-1
    		  
    Published by Shannan Muskopf
  • HS-LS3.A: Inheritance of Traits Lab Experiment
    Transcription and Translation Lab - From Gene to Protein
    Free Student Handout
    Free Teacher Notes
     
    Lab
    In this transcription and translation lab, students learn how a gene provides the instructions for making a protein, and how a mutation in the gene for sickle cell hemoglobin can result in sickle cell anemia. Students use paper models to transcribe and translate the DNA into a protein.
    NGSS Standard
    HS-LS1-1
    HS-LS3-1
    HS-LS3-2
    MS-LS3-1 (Mutations)
    		  
    Published by Ingrid Waldron and Jennifer Doherty
  • HS-LS3.A: Inheritance of Traits Lab Experiment
    DNA Extraction Lab
    Free Student Handout
    Free Teacher Notes
     
    Lab
    In this DNA lab, students extract DNA from their cheek cells to learn about the structure of DNA and DNA replication. The lab has students think about why they were using each reagent and how that relates to the polarity of lipids. Students answer questions regarding DNA base pairing and it relates to the central dogma (DNA - Proteins - Traits).
    NGSS Standard
    HS-LS1-1
    HS-LS3-1
    		  
    Published by Ingrid Waldron and Jennifer Doherty
  • HS-LS3.A: Inheritance of Traits Lab Experiment
    Chromosome Modeling Lab - Mitosis, Meiosis and Fertilization
    Free Student Handout
    Free Teacher Notes
     
    Lab
    In this chromosome modeling lab, students create pairs of socks models of chromosomes to model the processes of mitosis, meiosis, and fertilization. Students also build a foundation about meiosis and fertilization and how it relates to genetics and genetic disorders.
    NGSS Standard
    HS-LS1-4
    HS-LS3-1
    HS-LS3-2
    		  
    Published by Ingrid Waldron and Jennifer Doherty
  • HS-LS3.A: Inheritance of Traits Project
    DNA to Me Lyrics Project
    Published by NGSS Life Science. Free Lesson Plan (PDF)

    Lesson Plan (DOCX) & Answer Key with Membership
     
    Project
    In this protein synthesis project, students will write a poem or music lyrics about DNA, protein synthesis, and phenotypes. This DNA project is a culmination of what students who have already learned about DNA structure, DNA base pairing, genes, transcription, translation, and phenotypes.
    NGSS Standard
    HS-LS1-1
    HS-LS1-6
    HS-LS3-1
    		  
    Published by NGSS Life Science
  • HS-LS3.A: Inheritance of Traits Lab Experiment
    Bacteria Transformation
    Free Lesson Plan
     
    Lab
    Students construct paper recombinant plasmids to simulate the methods genetic engineers use to create modified bacteria. They learn what role restriction enzymes, DNA ligase, and genes play in the modification of organisms. This activity will use the insulin gene and combine it with a bacteria's gene sequence (plasmid DNA) for the production of the protein insulin for medicine.
    NGSS Standard
    HS-LS3-1
    		  
    Published by Teach Engineering
  • Multimedia
    Cracking the Code of Life
    Free Video
     
    Multimedia
    This NOVA video covers topics including the human genome, mutations, genetic variations, the supreme court decision to patent genes, finding cures to diseases, and genetic modification.
    NGSS Standard
    HS-LS3-1
    		  
    Published by WGBH Educational Foundation and Clear Blue Sky Productions
  • HS-LS3.A: Inheritance of Traits Lab Experiment
    Gene Expression - Ghost in Your Genes
    Free Lesson Plan
    Free Video
     
    Lab
    Students model how scientists use DNA microarrays to determine levels of gene expression in breast cancer patients, and then choose treatments based on what they learn.
    NGSS Standard
    HS-LS1-1
    HS-LS3-1
    		  
    Published by Margy Kuntz and NOVA / PBS
  • HS-LS3.A: Inheritance of Traits Test / Quiz
    DNA Structure Quiz
    Published by NGSS Life Science. Free Lesson Plan (PDF)

    Lesson Plan (DOCX) & Answer Key with Membership
     
    Test
    With this DNA structure quiz, students’ knowledge of the structure of DNA is assessed. Topics include double helix, nucleotide monomers, DNA polymers, nucleic acids biomolecules, DNA replication, complementary strands and base pairing, deoxyribose sugar and phosphate backbone, and nitrogen bases, adenine, guanine, cytosine, thymine.
    NGSS Standard
    HS-LS1-6
    HS-LS3-1
    		  
    Published by NGSS Life Science
  • HS-LS3.A: Inheritance of Traits Worksheet Recently Updated
    Diploid vs Haploid Worksheet
    Published by NGSS Life Science. Free Lesson Plan (PDF)

    Lesson Plan (DOCX) & Answer Key with Membership
     
    Worksheet
    In this meiosis chromosome worksheet, students answer questions about the number of chromosomes generated by either mitosis or meiosis. Haploid and diploid chromosome numbers help students understand the reproduction type used in each process.
    NGSS Standard
    HS-LS1-4
    HS-LS3-1
    HS-LS3-2
    MS-LS3-2 (Types of Reproduction)
    		  
    Published by NGSS Life Science
  • HS-LS3.A: Inheritance of Traits Lab Experiment
    Double Helix Modeling Lab
    Published by NGSS Life Science. Free Lesson Plan (PDF)

    Lesson Plan (DOCX) & Answer Key with Membership
     
    Lab
    In this DNA modeling lab, students build a paper model of the double helix. Students label the DNA molecule with the four DNA nucleotides and practice nitrogen base paring. At the end of class, students can attach all the models and twist and coil them to simulate super coiling.
    NGSS Standard
    HS-LS3-1
    		  
    Published by NGSS Life Science

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